Race
dimanche 2 mai 2021, 12h01 GMT – 12h43 GMT
| Nom | Équipe | Temps | |
|---|---|---|---|
| 1 |  Jack Miller | Ducati Lenovo Team | 41′ 5.602″ |
| 2 | Francesco Bagnaia | Ducati Lenovo Team | + 1.912″ |
| 3 | Franco Morbidelli | Petronas Yamaha SRT | + 2.516″ |
| 4 | Takaaki Nakagami | LCR Honda IDEMITSU | + 3.206″ |
| 5 | Joan Mir | Team SUZUKI ECSTAR | + 4.256″ |
| 6 | Aleix Espargaró | Aprilia Racing Team Gresini | + 5.164″ |
| 7 | Maverick Viñales | Monster Energy Yamaha MotoGP | + 5.651″ |
| 8 | Johann Zarco | Pramac Racing | + 7.161″ |
| 9 | Marc Márquez | Repsol Honda Team | + 10.494″ |
| 10 | Pol Espargaró | Repsol Honda Team | + 11.776″ |
| 11 | Miguel Oliveira | Red Bull KTM Factory Racing | + 14.766″ |
| 12 | Stefan Bradl | Team HRC | + 17.243″ |
| 13 |  Fabio Quartararo | Monster Energy Yamaha MotoGP | + 18.907″ |
| 14 | Danilo Petrucci | Tech3 KTM Factory Racing | + 20.095″ |
| 15 | Luca Marini | SKY VR46 Avintia | + 20.922″ |
| 16 |  Valentino Rossi | Petronas Yamaha SRT | + 22.731″ |
| 17 | Iker Lecuona | Tech3 KTM Factory Racing | + 23.277″ |
| 18 | Tito Rabat | Pramac Racing | + 30.314″ |
| 19 | Lorenzo Salvadori | Aprilia Racing Team Gresini | + 37.912″ |
| 20 | Álex Rins | Team SUZUKI ECSTAR | + 38.234″ |