Race
dimanche 24 octobre 2021, 12h00 GMT – 12h44 GMT
| Nom | Équipe | Temps | |
|---|---|---|---|
| 1 |  Marc Márquez | Repsol Honda Team | 41′ 52.83″ |
| 2 | Pol Espargaró | Repsol Honda Team | + 4.859″ |
| 3 | Enea Bastianini | Avintia Esponsorama | + 12.013″ |
| 4 |  Fabio Quartararo | Monster Energy Yamaha MotoGP | + 12.775″ |
| 5 | Johann Zarco | Pramac Racing | + 16.458″ |
| 6 | Álex Rins | Team SUZUKI ECSTAR | + 17.669″ |
| 7 | Aleix Espargaró | Aprilia Racing Team Gresini | + 18.468″ |
| 8 | Maverick Viñales | Aprilia Racing Team Gresini | + 18.607″ |
| 9 | Luca Marini | SKY VR46 Avintia | + 25.417″ |
| 10 |  Valentino Rossi | Petronas Yamaha SRT | + 27.735″ |
| 11 | Brad Binder | Red Bull KTM Factory Racing | + 27.879″ |
| 12 | Michele Pirro | Ducati Lenovo Team | + 28.137″ |
| 13 | Andrea Dovizioso | Petronas Yamaha SRT | + 41.413″ |
| 14 | Franco Morbidelli | Monster Energy Yamaha MotoGP | + 42.83″ |
| 15 | Takaaki Nakagami | LCR Honda IDEMITSU | + 1′ 22.462″ |